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p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging.

PLoS ONE. 2017;

Tormos Ana M，Rius-Pérez Sergio，Jorques María，Rada Patricia，Ramirez Lorena，Valverde ángela M，Nebreda ángel R，Sastre Juan，Taléns-Visconti Ra

Products/Services Used	Details	Operation
Catalog Antibody	). Antibodies used were as follows: AKT (Genscript A00301); α tubulin (Sigma Aldrich T6074); cyclin	Get A Quote

摘要

Hepatocyte poliploidization is an age-dependent process， being cytokinesis failure the main mechanism of polyploid hepatocyte formation. Our aim was to study the role of p38α MAPK in the regulation of actin cytoskeleton and cytokinesis in hepatocytes during development and aging.