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Structure of the human KMN complex and implications for regulation of its assembly

Authors: Soumitra Polley,?Tobias Raisch,?Sabrina Ghetti,?Marie K?rner,?Melina Terbeck,?Frauke Gr?ter,?Stefan Raunser,?Camilo Aponte-Santamaría,?Ingrid R Vetter,?Andrea Musacchio

Journal: NATURE STRUCTURAL & MOLECULAR BIOLOGY

PubMed ID: 38459128

Doi: 10.1038/s41594-024-01230-9

Products & Services: Peptide Synthesis

PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport

Authors: Paraskevi Tziortzouda?,?Jolien Steyaert?,?Wendy Scheveneels?,?Adria Sicart?,?Katarina Stoklund Dittlau?,?Adriana Margarida Barbosa Correia?,?Thibaut Burg?,?Arun Pal?,?Andreas Hermann?,?Philip Van Damme?,?Thomas G Moens?,?Ludo Van Den Bosch

Journal: Acta Neuropathol

PubMed ID: 38363426

Doi: 10.1007/s00401-024-02689-y

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Local structural preferences in shaping tau amyloid polymorphism

Authors: Nikolaos Louros , Martin Wilkinson , Grigoria Tsaka , Meine Ramakers , Chiara Morelli , Teresa Garcia , Rodrigo Gallardo , Sam D'Haeyer , Vera Goossens , Dominique Audenaert , Dietmar Rudolf Thal , Ian R Mackenzie , Rosa Rademakers , Neil A Ranson , Sheena E Radford , Frederic Rousseau , Joost Schymkowitz

Journal: Nat Commun

PubMed ID: 38310108

Doi: 10.1038/s41467-024-45429-2

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GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease

Authors: Meitian Wang, Xiuqing He, Jie Li, Daobin Han, Pan You, Hui Yu, Luwen Wang, Bo Su

Journal: Biochim Biophys Acta Mol Basis Dis

PubMed ID: 38382624

Doi: 10.1016/j.bbadis.2024.167093

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ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis

Authors: Yongbing Yang , Yanan Wang , Zhongcheng Wang , Huanyu Yan , Yi Gong , Yingchao Hu , Yuying Jiang , Shuang Wen , Feifei Xu , Bingwei Wang , Fiachra Humphries , Yun Chen , Xi Wang , Shuo Yang

Journal: Nat Cell Biol .

PubMed ID: 38326554

Doi: 10.1038/s41556-024-01351-9

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Prediction of anticancer peptides derived from the true lectins of Phoenix dactylifera and their synergetic effect with mitotane

Authors: Othman Baothman, Ehab M. M. Ali , Salman Hosawi , Emadeldin Hassan E. Konoz, Isam M. Abu Zeid, Abrar Ahmadand Hisham N. Altayb

Journal: Frontiers in pharmacology

Doi: 10.3389/fphar.2024.1322865

Products & Services: Peptide Synthesis

Cryo-EM structures of the plant plastid-encoded RNA polymerase

Authors: Xiao-Xian Wu, Wen-Hui Mu, Fan Li, Shu-Yi Sun, Chao-Jun Cui , Chanhong Kim, Fei Zhou , Yu Zhang

Journal: Cell

PubMed ID: 38428393

Doi: 10.1016/j.cell.2024.01.026

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Nanobody-Mediated Dualsteric Engagement of the Angiotensin Receptor Broadens Biased Ligand Pharmacology

Authors: Nayara Braga Emidio , Brandi M Small , Amanda R Keller , Ross W Cheloha , Laura M Wingler

Journal: Mol Pharmacol

PubMed ID: 38164609

Doi: 10.1124/molpharm.123.000797

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Neuroprotective effects of annexin A1 tripeptide in rats with sepsis-associated encephalopathy

Authors: Qiao Cui, Nannan Qin, Yonghan Zhang, Yanmei Miao, Leiyu Xie, Xinglong Ma, Zhiquan Zhang, Peng Xie

Journal: Biotechnol Appl Biochem

PubMed ID: 38409880

Doi: 10.1002/bab.2569

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Determinants of viscoelasticity and flow activation energy in biomolecular condensates

Authors: Ibraheem Alshareedah , Anurag Singh , Sean Yang , Vysakh Ramachandran , Alexander Quinn , Davit A Potoyan , Priya R Banerjee

Journal: SCIENCE ADVANCES

PubMed ID: 38363841

Doi: 10.1126/sciadv.adi6539

Products & Services: Peptide Synthesis

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