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Antibody response to second dose of the BNT162b2 mRNA vaccine in the first 12?weeks in South Korea: A prospective longitudinal study

Vaccine. 2021-12;

Hyun Jin Kim, Heon Jeong Yun, Jungok Kim, Sungmin Kym, Qute Choi

Products/Services Used	Details	Operation
Protein Reagents and Products	… Neutralising antibody tests were manually performed using a commercially available surrogate virus neutralisation assay (sVNT, Genscript, Netherlands) according to the?… We performed the COVID-19 IgM/IgG Combo test for the anti-SARS-CoV-2 binding antibodies, which?…	Get A Quote

摘要

objective: To characterise the antibody response for 12?weeks following second dose of the Pfizer/BioNTech BNT162b2 mRNA vaccine in hospital workers of a Korean general hospital. methods: We measured the level of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-receptor binding domain (anti-RBD) and neutralising antibodies every week in the first 4?weeks, and at weeks 8 and 12 following the second dose of vaccination in 71 hospital workers. results: The initial median level of anti-RBD and neutralising antibodies were 3898.0 U/mL (interquartile range [IQR], 2107.5-5478.5) and 97.54 % (IQR, 96.85-97.81), respectively. The levels declined the fastest and the most significantly between weeks 1 a... More