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Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization

Authors: Edward A Partlow, Kevin S Cannon, Gunther Hollopeter, Richard W Baker

Journal: Nat Struct Mol Biol

PubMed ID: 35347313

Doi: 10.1038/s41594-022-00749-z

Products & Services: Peptide Synthesis

Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination

Authors: Jon Riise, Saskia Meyer, Isaac Blaas, Adity Chopra, Trung T Tran, Marina Delic-Sarac, Malu Lian Hestdalen, Ellen Brodin, Even Holth Rustad, Ke-Zheng Dai, John Torgils Vaage, Lise Sofie Haug Nissen-Meyer, Fredrik Sund, Karin F Wader, Anne T Bjornevik, Peter A Meyer, Gro O Nygaard, Marton K?nig, Sigbj?rn Smeland, Fridtjof Lund-Johansen, Johanna Olweus, Arne Kolstad

Journal: Br J Haematol

PubMed ID: 35254660

Doi: 10.1111/bjh.18149

Products & Services: Peptide Synthesis

Phosphoproteome Analysis Identifies a Synaptotagmin-1-Associated Complex Involved in Ischemic Neuron Injury

Authors: Wei Jiang, Pei Zhang, Peng Yang, Na Kang, Junqiang Liu, Yilixiati Aihemaiti, Haijun Tu

Journal: Mol Cell Proteomics

PubMed ID: 35257887

Doi: 10.1016/j.mcpro.2022.100222

Products & Services: Peptide Synthesis

Highly Specific Monoclonal Antibody Targeting the Botulinum Neurotoxin Type E Exposed SNAP-25 Neoepitope

Authors: Adva Mechaly, Eran Diamant, Ron Alcalay, Alon Ben David, Eyal Dor, Amram Torgeman, Ada Barnea, Meni Girshengorn, Lilach Levin, Eyal Epstein, Ariel Tennenhouse, Sarel J Fleishman, Ran Zichel, Ohad Mazor

Journal: Antibodies (Basel)

PubMed ID: 35323195

Doi: 10.3390/antib11010021

Products & Services: Peptide Synthesis

Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling

Authors: Maricel Gomez-Soler, Marina P. Gehring, Bernhard C. Lechtenberg,Elmer Zapata-Mercado, Alyssa Ruelos,Mike W. Matsumoto,Kalina Hristova,and Elena B. Pasquale

Journal: iScience

Doi: doi.org/10.1016/j.isci.2022.103870

Products & Services: Peptide Synthesis

Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression

Authors: Yvonne E Smith, Guannan Wang, Ciara L Flynn, Stephen F Madden, Owen MacEneaney, Rodrigo G B Cruz, Cathy E Richards, Hanne Jahns, Marian Brennan, Mattia Cremona, Bryan T Hennessy, Katherine Sheehan, Alexander Casucci, Faizah A Sani, Lance Hudson, Joanna Fay, Sri H Vellanki, Siobhan O'Flaherty, Marc Devocelle, Arnold D K Hill, Kieran Brennan, Saraswati Sukumar, Ann M Hopkins

Journal: Cancers (Basel)

PubMed ID: 35267611

Doi: 10.3390/cancers14051303

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Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules

Authors: Hui Jin, Kazuki Kishida, Noriko Arase, Sumiko Matsuoka, Wataru Nakai, Masako Kohyama, Tadahiro Suenaga, Ken Yamamoto, Takehiko Sasazuki, Hisashi Arase

Journal: Sci Adv

PubMed ID: 35245125

Doi: 10.1126/sciadv.abj9867

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An In Vivo Screen to Identify Short Peptide Mimotopes with Enhanced Antitumor Immunogenicity

Authors: Xuedan He, Shiqi Zhou, Breandan Quinn, Dushyant Jahagirdar, Joaquin Ortega, Mark D Long, Scott I Abrams, Jonathan F Lovell

Journal: Cancer Immunol Res

PubMed ID: 34992135

Doi: 10.1158/2326-6066.CIR-21-0332

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Novel Secreted Peptides From var With Immunomodulatory Effects That Enhance Fungal Pathogenesis

Authors: Sameh S M Soliman, Eman M El-Labbad, Ameera Abu-Qiyas, Bahgat Fayed, Alshaimaa M Hamoda, Ahmed M Al-Rawi, Salam Dakalbab, Abdel-Nasser A El-Shorbagi, Mawieh Hamad, Ashraf S Ibrahim, Mohammad G Mohammad

Journal: Front Microbiol

PubMed ID: 35387075

Doi: 10.3389/fmicb.2022.863133

Products & Services: Peptide Synthesis

Symmetric and asymmetric receptor conformation continuum induced by a new insulin

Authors: Xiaochun Xiong, Alan Blakely, Jin Hwan Kim, John G Menting, Ingmar B Sch?fer, Heidi L Schubert, Rahul Agrawal, Theresia Gutmann, Carlie Delaine, Yi Wolf Zhang, Gizem Olay Artik, Allanah Merriman, Debbie Eckert, Michael C Lawrence, ünal Coskun, Simon J Fisher, Briony E Forbes, Helena Safavi-Hemami, Christopher P Hill, Danny Hung-Chieh Chou

Journal: Nat Chem Biol

PubMed ID: 35289328

Doi: 10.1038/s41589-022-00981-0

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