国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging

J Neuroinflammation. 2024-06; 
Seokjo Kang, Emily Y Ko, Amelia E Andrews, Juliana E Shin, Karina J Nance, Pijus K Barman, Peter S Heeger, Willard M Freeman, Bérénice A Benayoun, Helen S Goodridge
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis … on 4–20% SurePage? gels (GenScript) in MOPS buffer (GenScript) and transferred to a PVDF … Altered expression of complement pathway components by old hippocampal microglia, … Get A Quote

摘要

Microglia, the brain's resident macrophages, maintain brain homeostasis and respond to injury and infection. During aging they undergo functional changes, but the underlying mechanisms and their contributions to neuroprotection versus neurodegeneration are unclear. Previous studies suggested that microglia are sex dimorphic, so we compared microglial aging in mice of both sexes. RNA-sequencing of hippocampal microglia revealed more aging-associated changes in female microglia than male microglia, and more sex differences in old microglia than young microglia. Pathway analyses and subsequent validation assays revealed a stronger AKT-mTOR-HIF1α-driven shift to glycolysis among old female microglia and indicated ... More

關鍵詞

Aging, Alzheimer’s disease, Microglia, Sex differences
              主站蜘蛛池模板: 莱芜市| 稻城县| 枣庄市| 静海县| 保德县| 万全县| 正宁县| 寻甸| 江山市| 龙胜| 夹江县| 延寿县| 泰顺县| 新营市| 漠河县| 合肥市| 中卫市| 江门市| 镇雄县| 邮箱| 民和| 福海县| 容城县| 大荔县| 新乡市| 井陉县| 特克斯县| 阿勒泰市| 略阳县| 庄河市| 巴南区| 洛南县| 凤台县| 玉门市| 当涂县| 虹口区| 开远市| 隆回县| 京山县| 绿春县| 迭部县|