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LncRNA FOXP4-AS1 Is Involved in Cervical Cancer Progression via Regulating miR-136-5p/CBX4 Axis

Onco Targets Ther. 2020-03-01; 
Juan Zhao, Ting Yang, Long Li
Products/Services Used Details Operation
Catalog Antibody … pcDNA3.1 contains sequence of FOXP4-AS1 (pFOXP4-AS1) and CBX4 (pCBX4) were purchased from GenScript (Nanjing, Jiangsu, China). Transfection of these molecules was conducted using Lipofectamine 2000 (Invitrogen). Quantitative Real-Time PCR (RT-qPCR) … Get A Quote

摘要

unassigned: Cervical cancer (CC) is a major health threat to women worldwide. Long non-coding RNA (lncRNA) has been reported to play crucial roles in regulating carcinogenesis, including CC. unassigned: In this work, levels of lncRNA forkhead box P4 antisense RNA 1 (FOXP4-AS1) in CC cell lines and normal cell lines were analyzed with quantitative Real-Time?Polymerase Chain Reaction (qRT-PCR) method. Effects of FOXP4-AS1 on CC cellular behaviors including proliferation, migration, and invasion were explored. Bioinformatic prediction tools and luciferase activity reporter assay were conducted to explore the downstream molecules for FOXP4-AS1. unassigned: We found FOXP4-AS1 expression was significantly higher in ... More

關鍵詞

CBX4, FOXP4-AS1, cervical cancer, miR-136-5p
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