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Global Landscape of Native Protein Complexes in Synechocystis sp PCC 6803

biorxiv. 2020; 
Chen?Xu, ?Bing?Wang, ?Lin?Yang, ?Lucas Zhongming?Hu, ?Lanxing?Yi, ?Yaxuan?Wang, ?Shenglan?Chen, Andrew?Emili, Cuihong?Wan
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摘要

Synechocystis?sp. PCC 6803 is a model organism for studying photosynthesis, energy metabolism, and environmental stress. Though known as the first fully sequenced phototrophic organism, Synechocystis sp. PCC 6803 still has almost half of its proteome without functional annotations. In this study, we obtained 291 protein complexes, including 24,092 protein-protein interactions (PPIs) among 2,062 proteins by using co–fractionation and LC/MS/MS. The additional level of PPIs information not only revealed the roles of photosynthesis in metabolism, cell motility, DNA repair, cell division, and other physiological processes, but also showed how protein functions vary from bacteria to higher plants due to the change... More

關(guān)鍵詞

Synechocystis sp. PCC 6803; Protein complexes; Protein-protein interaction; Photosynthesis; Cyanobacterium
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