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MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models

Authors: Douglas D Fang, Qiuqiong Tang, Yanhui Kong, Tao Rong, Qixin Wang, Na Li, Xu Fang, Jiaxing Gu, Dengkun Xiong, Yan Yin, Jing Deng, Dajun Yang, Yifan Zhai

Journal: Cell Death Discov

PubMed ID: 33941774

Doi: 10.1038/s41420-021-00465-5

Products & Services: Proteins, Expression, Isolation and Analysis

Clinical Utility of Biosensing Platforms for Confirmation of SARS-CoV-2 Infection

Authors: Le Minh Tu Phan, My-Van Tieu, Thi-Thu Pham, Sungbo Cho

Journal: Biosensors (Basel)

PubMed ID: 34073756

Doi: 10.3390/bios11060167

Products & Services: Proteins, Expression, Isolation and Analysis

Coevolution of ribosomal RNA expansion segment 7L and assembly factor Noc2p specializes the ribosome biogenesis pathway between Saccharomyces cerevisiae and Candida albicans

Authors: Xiangxiang Wang, Zhiyong Yue, Feifei Xu, Sufang Wang, Xin Hu, Junbiao Dai, Guanghou Zhao

Journal: Nucleic Acids Res

PubMed ID: 33823547

Doi: 10.1093/nar/gkab218

Products & Services: Proteins, Expression, Isolation and Analysis

Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression

Authors: Miljenko V Panajatovic, Francois Singh, Stephan Kr?henbühl, Jamal Bouitbir

Journal: Int J Mol Sci

PubMed ID: 34066911

Doi: 10.3390/ijms22094950

Products & Services: Proteins, Expression, Isolation and Analysis

Activity of immunoproteasome inhibitor ONX-0914 in acute lymphoblastic leukemia expressing MLL-AF4 fusion protein

Authors: Tyler W Jenkins, Sondra L Downey-Kopyscinski, Jennifer L Fields, Gilbert J Rahme, William C Colley, Mark A Israel, Andrey V Maksimenko, Steven N Fiering, Alexei F Kisselev

Journal: Sci Rep

PubMed ID: 34035431

Doi: 10.1038/s41598-021-90451-9

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of the SARS-CoV-2 Neutralization Potential of COVID-19-Convalescent Donors

Authors: Bernd Jahrsd?rfer, Rüdiger Gro?, Alina Seidel, Lukas Wettstein, Carolin Ludwig, Tatjana Schwarz, Sixten K?rper, Markus Rojewski, Ramin Lotfi, Christoph Weinstock, Erhard Seifried, Victor Max Corman, Christian Drosten, Jan Münch, Hubert Schrezenmeier

Journal: J Immunol

PubMed ID: 33980583

Doi: 10.4049/jimmunol.2100036

Products & Services: Proteins, Expression, Isolation and Analysis

Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential

Authors: Nelson Ferreira, Hjalte Gram, Zachary A Sorrentino, Emil Gregersen, Sissel Ida Schmidt, Lasse Reimer, Cristine Betzer, Clara Perez-Gozalbo, Marjo Beltoja, Madhu Nagaraj, Jie Wang, Jan S Nowak, Mingdong Dong, Katarina Willén, Ersoy Cholak, Kaare Bjerregaard-Andersen, Nicolas Mendez, Prakruti Rabadia, Mohammad Shahnawaz, Claudio Soto, Daniel E Otzen, ümit Akbey, Morten Meyer, Benoit I Giasson, Marina Romero-Ramos, Poul Henning Jensen

Journal: Acta Neuropathol

PubMed ID: 33978813

Doi: 10.1007/s00401-021-02316-0

Products & Services: Proteins, Expression, Isolation and Analysis

Effects of Atypical Antipsychotics, Clozapine, Quetiapine and Brexpiprazole on Astroglial Transmission Associated with Connexin43

Authors: Kouji Fukuyama, Motohiro Okada

Journal: Int J Mol Sci

PubMed ID: 34070699

Doi: 10.3390/ijms22115623

Products & Services: Proteins, Expression, Isolation and Analysis

Two bHLH transcription factors, bHLH48 and bHLH60, associate with phytochrome interacting factor 7 to regulate hypocotyl elongation in Arabidopsis

Authors: Chuanwei Yang, Sha Huang, Yue Zeng, Chang Liu, Qinyi Ma, Jose Pruneda-Paz, Steve A Kay, Lin Li