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Antigen modifications improve nucleoside-modified mRNA-based influenza virus vaccines in mice

Authors: Alec W Freyn, Matthew Pine, Victoria C Rosado, Marcel Benz, Hiromi Muramatsu, Mitchell Beattie, Ying K Tam, Florian Krammer, Peter Palese, Raffael Nachbagauer, Meagan McMahon, Norbert Pardi

Journal: Mol Ther Methods Clin Dev

PubMed ID: 34485597

Doi: 10.1016/j.omtm.2021.06.003

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Characterization of the substrate binding site of an iron detoxifying membrane transporter from Plasmodium falciparum

Authors: Pragya Sharma, Veronika Tóth, Edel M Hyland, Christopher J Law

Journal: Malar J

PubMed ID: 34193175

Doi: 10.1186/s12936-021-03827-7

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Epigenomic Landscape of Lyme Disease Spirochetes Reveals Novel Motifs

Authors: Jenny Wachter, Craig Martens, Kent Barbian, Ryan O M Rego, Patricia Rosa

Journal: MBio

PubMed ID: 34156261

Doi: 10.1128/mBio.01288-21

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Immunoinformatics and molecular dynamics approaches: Next generation vaccine design against West Nile virus

Authors: Md Tahsin Khan, Rahatul Islam, Tarhima Jahan Jerin, Araf Mahmud, Sahara Khatun, Ahasanul Kobir, Md Nahidul Islam, Arzuba Akter, Shakhinur Islam Mondal

Journal: PLoS ONE

PubMed ID: 34138958

Doi: 10.1371/journal.pone.0253393

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Dengue virus-free defective interfering particles have potent and broad anti-dengue virus activity

Authors: Dongsheng Li, Min-Hsuan Lin, Daniel J Rawle, Hongping Jin, Zhonglan Wu, Lu Wang, Mary Lor, Mazhar Hussain, John Aaskov, David Harrich

Journal: Commun Biol

PubMed ID: 33976375

Doi: 10.1038/s42003-021-02064-7

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Allostery through DNA drives phenotype switching

Authors: Gabriel Rosenblum, Nadav Elad, Haim Rozenberg, Felix Wiggers, Jakub Jungwirth, Hagen Hofmann

Journal: Nat Commun

PubMed ID: 34016970

Doi: 10.1038/s41467-021-23148-2

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Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages

Authors: Florian Wanke, Simon Gutbier, Anna Rümmelin, Malte Steinberg, Lindsey D Hughes, Mascha Koenen, Juliana Komuczki, Daniel Regan-Komito, Sagie Wagage, Julia Hesselmann, Ralf Thoma, Doris Brugger, Tony Christopeit, Hayian Wang, Floriane Point, Remy Hallet, Sourav Ghosh, Carla V Rothlin, Christoph Patsch, Barbara Geering

Journal: Cell Death Dis

PubMed ID: 34035216

Doi: 10.1038/s41419-021-03770-0

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The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains

Authors: Vladimir Zhemkov , Jonathon A Ditlev , Wan-Ru Lee , Mikaela Wilson , Jen Liou , Michael K Rosen , Ilya Bezprozvanny

Journal: Elife

PubMed ID: 33973848

Doi: 10.7554/eLife.65192

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Co-occupancy identifies transcription factor co-operation for axon growth

Authors: Ishwariya Venkatesh, Vatsal Mehra, Zimei Wang, Matthew T Simpson, Erik Eastwood, Advaita Chakraborty, Zac Beine, Derek Gross, Michael Cabahug, Greta Olson, Murray G Blackmore

Journal: Nat Commun

PubMed ID: 33953205

Doi: 10.1038/s41467-021-22828-3

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Charge Regulation during Amyloid Formation of α-Synuclein

Authors: Tinna Pálmadóttir, Anders Malmendal, Thom Leiding, Mikael Lund, Sara Linse

Journal: J Am Chem Soc

PubMed ID: 33998793

Doi: 10.1021/jacs.1c01925

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