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Generation and utility of a single-chain fragment variable monoclonal antibody platform against a baculovirus expressed recombinant receptor binding domain of SARS-CoV-2 spike protein
Authors: Reda Salem, Alaa A El-Kholy, Fatma R Waly, Dalia Ayman, Aya Sakr, Mai Hussein
Journal: Mol Immunol
PubMed ID: 34915268
Doi: 10.1016/j.molimm.2021.12.006
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Deep mutational scanning for therapeutic antibody engineering
Authors: Kyrin R Hanning, Mason Minot, Annmaree K Warrender, William Kelton, Sai T Reddy
Journal: Trends Pharmacol Sci
PubMed ID: 34895944
Doi: 10.1016/j.tips.2021.11.010
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Novel sequential immunocapture microflow LC/MS/MS approach to measuring PTH-Fc protein in human serum
Authors: Haixing Wang, Jiang Wu, Peng Pan, Thuy Nguyen, Michael Cwik, Ling Morgan
Journal: Bioanalysis
PubMed ID: 34894717
Doi: 10.4155/bio-2021-0233
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Developing a secretory AcGFP1-based IRES expression system for efficient production of mammalian recombinant proteins
Authors: Zhongcheng Zou, Matthew Spencer, Peter D Sun
Journal: Protein Expr Purif
PubMed ID: 34920134
Doi: 10.1016/j.pep.2021.106029
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Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2
Authors: Yannick Galipeau, Vinayakumar Siragam, Geneviève Laroche, Erika Marion, Matthew Greig, Michaeline McGuinty, Ronald A Booth, Yves Durocher, Miroslava Cuperlovic-Culf, Steffany A L Bennett, Angela M Crawley, Patrick M Giguère, Curtis Cooper, Marc-André Langlois
Journal: EBioMedicine
PubMed ID: 34861490
Doi: 10.1016/j.ebiom.2021.103700
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The Marine Neurotoxin Brevetoxin (PbTx-2) Inhibits and Mammalian Thioredoxin Reductases by Targeting Different Residues
Authors: Ricardo Colon, Michelle Wheater, Emily J Joyce, Emma J Ste Marie, Robert J Hondal, Kathleen S Rein
Journal: J Nat Prod
PubMed ID: 34752085
Doi: 10.1021/acs.jnatprod.1c00795
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Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs
Authors: Sophie M-C Gobeil, Benjamin G Bobay, Praveen R Juvvadi, D Christopher Cole, Joseph Heitman, William J Steinbach, Ronald A Venters, Leonard D Spicer
Journal: MBio
PubMed ID: 34809463
Doi: 10.1128/mBio.03000-21
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Immuno-transcriptomic profiling of extracranial pediatric solid malignancies
Authors: Andrew S Brohl, Sivasish Sindiri, Jun S Wei, David Milewski, Hsien-Chao Chou, Young K Song, Xinyu Wen, Jeetendra Kumar, Hue V Reardon, Uma S Mudunuri, Jack R Collins, Sushma Nagaraj, Vineela Gangalapudi, Manoj Tyagi, Yuelin J Zhu, Katherine E Masih, Marielle E Yohe, Jack F Shern, Yue Qi, Udayan Guha, Daniel Catchpoole, Rimas J Orentas, Igor B Kuznetsov, Nicolas J Llosa, John A Ligon, Brian K Turpin, Daniel G Leino, Shintaro Iwata, Irene L Andrulis, Jay S Wunder, Silvia R C Toledo, Paul S Meltzer, Ching Lau, Beverly A Teicher, Heather Magnan, Marc Ladanyi, Javed Khan
Journal: Cell Rep
PubMed ID: 34818552
Doi: 10.1016/j.celrep.2021.110047
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Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein
Authors: Mary C Andorfer, Lindsey R F Backman, Phoebe L Li, Emily C Ulrich, Catherine L Drennan
Journal: J Biol Chem
PubMed ID: 34801558
Doi: 10.1016/j.jbc.2021.101423
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Engineering Cupriavidus necator DSM 545 for the one-step conversion of starchy waste into polyhydroxyalkanoates
Authors: Silvia Brojanigo, Nicoletta Gronchi, Tiziano Cazzorla, Tuck Seng Wong, Marina Basaglia, Lorenzo Favaro, Sergio Casella
Journal: Bioresour Technol
PubMed ID: 34808314
Doi: 10.1016/j.biortech.2021.126383
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