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A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity

Authors: Pedersen H, Jensen RK, Jensen JMB, Fox R, Pedersen DV, Olesen HG, Hansen AG, Christiansen D, Mazarakis SMM, Lojek N, Hansen P, Gadeberg TAF, Zarantonello A, Laursen NS, Mollnes TE, Johnson MB, Stevens B, Thiel S, Andersen GR

Journal: Journal of immunology (Baltimore, Md. : 1950)

PubMed ID: 32938727

Doi: 10.4049/jimmunol.2000752

Products & Services: Stable Cell Lines

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

Authors: Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC

Journal: Nature Cell Biology

PubMed ID: 32929201

Doi: 10.1038/s41556-020-0575-z

Products & Services: Stable Cell Lines

Proteolytic cleavage of Slit by the Tolkin protease converts an axon repulsion cue to an axon growth cue in vivo

Authors: Kellermeyer R, Heydman LM, Gillis T, Mastick GS, Song M, Kidd T

Journal: Development (Cambridge, England)

PubMed ID: 32994163

Doi: 10.1242/dev.196055

Products & Services: Stable Cell Lines

The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils

Authors: Thacker D, Sanagavarapu K, Frohm B, Meisl G, Knowles TPJ, Linse S

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 33004626

Doi: 10.1073/pnas.2002956117

Products & Services: Stable Cell Lines

Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery

Authors: Tsou LK, Yeh SH, Ueng SH, Chang CP, Song JS, Wu MH, Chang HF, Chen SR, Shih C, Chen CT, Ke YY

Journal: Scientific REPORTS

PubMed ID: 33033310

Doi: 10.1038/s41598-020-73681-1

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Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide

Authors: Min K, Yoon HJ, Park JY, Baidya M, Dwivedi-Agnihotri H, Maharana J, Chaturvedi M, Chung KY, Shukla AK, Lee HH

Journal: Structure (London, England : 1993)

PubMed ID: 32579945

Doi: 10.1016/j.str.2020.06.002

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TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis

Authors: Damal Villivalam S, You D, Kim J, Lim HW, Xiao H, Zushin PH, Oguri Y, Amin P, Kang S

Journal: Nature Communications

PubMed ID: 32855402

Doi: 10.1038/s41467-020-18054-y

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Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development

Authors: Postlmayr A, Dumeau CE, Wutz A

Journal: Development (Cambridge, England)

PubMed ID: 32439758

Doi: 10.1242/dev.175141

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CD39 Produced from Human GMSCs Regulates the Balance of Osteoclasts and Osteoblasts through the Wnt/β-Catenin Pathway in Osteoporosis

Authors: Wu W, Xiao Z, Chen Y, Deng Y, Zeng D, Liu Y, Huang F, Wang J, Liu Y, Bellanti JA, Rong L, Zheng SG

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

PubMed ID: 32304668

Doi: 10.1016/j.ymthe.2020.04.003

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Surface Tethering of Inflammation-Modulatory Nanostimulators to Stem Cells for Ischemic Muscle Repair

Authors: Leong J, Hong YT, Wu YF, Ko E, Dvoretskiy S, Teo JY, Kim BS, Kim K, Jeon H, Boppart M, Yang YY, Kong H

Journal: ACS Nano

PubMed ID: 32243129

Doi: 10.1021/acsnano.9b04926

Products & Services: Stable Cell Lines

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