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Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library

Authors: Gibbons GS, Chakraborty A, Grigsby SM, Umeano AC, Liao C, Moukha-Chafiq O, Pathak V, Mathew B, Lee YT, Dou Y, Schürer SC, Reynolds RC, Snowden TS, Nikolovska-Coleska Z

Journal: European Journal of Medicinal Chemistry

PubMed ID: 31978781

Doi: 10.1016/j.ejmech.2019.112023

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[Preventive and Therapeutic Effects of Exogenous Apelin Regulating Autophagy on the Formation of Pulmonary Artery Hhypertension in Rats]

Authors: Yong-Ying Gou, Dong Liu, Gang Li, Ya-Nan Hu, Peng Jia, Han-Min Liu, Biu Liu

Journal: Sichuan Da Xue Xue Bao Yi Xue Ban

PubMed ID: 32220187

Doi: 10.12182/20200360205

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Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer

Authors: Yan Zhang, Andrei Pavlov, Sohail Malik, Hong Chen, Nancy Kim, Ziqing Li, Xiaohong Zhang, Melvin L DePamphilis, Robert G Roeder, Hui Ge

Journal: PLoS ONE

PubMed ID: 32231397

Doi: 10.1371/journal.pone.0230670

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The uncharacterized gene EVE contributes to vessel element dimensions in Populus

Authors: Ribeiro CL, Conde D, Balmant KM, Dervinis C, Johnson MG, McGrath AP, Szewczyk P, Unda F, Finegan CA, Schmidt HW, Miles B, Drost DR, Novaes E, Gonzalez-Benecke CA, Peter GF, Burleigh JG, Martin TA, Mansfield SD, Chang G, Wickett NJ, Kirst M

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 32041869

Doi: 10.1073/pnas.1912434117

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The Multifunctional Long-Distance Movement Protein of Pea Enation Mosaic Virus 2 Protects Viral and Host Transcripts from Nonsense-Mediated Decay

Authors: May JP,?Johnson PZ,?Ilyas M,?Gao F,?Simon AE

Journal: MBio

PubMed ID: 32156817

Doi: 10.1128/mBio.00204-20

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Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

Authors: Zhang T, Yin C, Boyd DF, Quarato G, Ingram JP, Shubina M, Ragan KB, Ishizuka T, Crawford JC, Tummers B, Rodriguez DA, Xue J, Peri S, Kaiser WJ, López CB, Xu Y, Upton JW, Thomas PG, Green DR, Balachandran S

Journal: Cell

PubMed ID: 32200799

Doi: 10.1016/j.cell.2020.02.050

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Inhibition of the Yersinia pestis Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis by α-Phenyl-Substituted Reverse Fosmidomycin Analogues

Authors: Ball HS, Girma M, Zainab M, Riley H, Behrendt CT, Lienau C, Konzuch S, Avelar LAA, Lungerich B, Soojhawon I, Noble SM, Kurz T, Couch RD

Journal: ACS Omega

PubMed ID: 32201804

Doi: 10.1021/acsomega.9b04171

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Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of Neural Network Activity through Non-Canonical p53 and Akt Signaling

Authors: Dai-Chi Liu, Stephanie Soriano, Yeeun Yook, Simon Lizarazo, Daphne E Eagleman, Nien-Pei Tsai

Journal: eNeuro

PubMed ID: 32161037

Doi: 10.1523/ENEURO.0438-19.2020

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ETV4 promotes the progression of gastric cancer through regulating KDM5D

Authors: L-S Cai, Q-X Chen, S-Y Fang, M-Q Lian, M-J Lian, M-Z Cai

Journal: Eur Rev Med Pharmacol Sci

PubMed ID: 32196595

Doi: 10.26355/eurrev_202003_20511

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A rare cause of severe Cushing's syndrome

Authors: Shamaila Zaman, Bijal Patel, Paul Glynne, Mark Vanderpump, Ali Alsafi, Sairah Khan, Rashpal Flora, Fausto Palazzo, Florian Wernig

Journal: Endocrinol Diabetes Metab Case Rep

PubMed ID: 32168466

Doi: 10.1530/EDM-20-0011

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