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Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies.
Authors: ArotcarenaMarie-Laure,BourdenxMathieu,DutheilNathalie,ThiolatMarie-Laure,DoudnikoffEvelyne,DoveroSandra,BallabioAndrea,FernagutPierre-Olivier,MeissnerWassilios G,BezardErwan,DehayBenj
Journal: JCI Insight
PubMed ID: 31434803
Doi: 10.1172/jci.insight.129719
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Deregulation of LRSAM1 expression impairs the levels of TSG101, UBE2N, VPS28, MDM2 and EGFR.
Authors: MinaidouAnna,NicolaouPaschalis,ChristodoulouKypr
Journal: PLoS ONE
PubMed ID: 30726272
Doi: 10.1371/journal.pone.0211814
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Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster.
Authors: XiaoChengfeng,QiuSh
Journal: Neurosci. Lett.
PubMed ID: 30528881
Doi: 10.1016/j.neulet.2018.12.009
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Coordination between stochastic and deterministic specification in the visual system.
Authors: Courgeon Maximilien,Desplan Cl
Journal: Science
PubMed ID: 31582524
Doi: 10.1126/science.aay6727
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Opposing signaling pathways regulate morphology in response to temperature in the fungal pathogen Histoplasma capsulatum.
Authors: Rodriguez Lauren,Voorhies Mark,Gilmore Sarah,Beyhan Sinem,Myint Anthony,Sil A
Journal: PLoS Biol
PubMed ID: 31568523
Doi: 10.1371/journal.pbio.3000168
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Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of β-arrestin2.
Authors: Luessen Deborah J,Sun Haiguo,McGinnis Molly M,Hagstrom Michael,Marrs Glen,McCool Brian A,Chen
Journal: J Biol Chem
PubMed ID: 31366729
Doi: 10.1074/jbc.RA118.006583
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GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells.
Authors: Xu Hao,Zhang Linshi,Qian Xiaohui,Zhou Xiaohu,Yan Yingcai,Zhou Jiarong,Ge Wenhao,Albahde Mugahed,Wang We
Journal: Exp Ther Med
PubMed ID: 31572509
Doi: 10.3892/etm.2019.7845
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Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination.
Authors: BoopathyArchana V,MandalAnasuya,KulpDaniel W,MenisSergey,BennettNitasha R,WatkinsHannah C,WangWade,MartinJacob T,ThaiNikki T,HeYanpu,SchiefWilliam R,HammondPaula T,IrvineDarre
Journal: Proc. Natl. Acad. Sci. U.S.A.
PubMed ID: 31358641
Doi: 10.1073/pnas.1902179116
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Requirement for memory B cell activation in protection from heterologous influenza virus reinfection.
Authors: LeachSarah,ShinnakasuRyo,AdachiYu,MomotaMasatoshi,Makino-OkamuraChieko,YamamotoTakuya,IshiiKen J,FukuyamaHidehiro,TakahashiYoshimasa,KurosakiTomo
Journal: Int. Immunol.
PubMed ID: 31231764
Doi: 10.1093/intimm/dxz049
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PD-L1 on invasive fibroblasts drives fibrosis in a humanized model of idiopathic pulmonary fibrosis.
Authors: GengYan,LiuXue,LiangJiurong,HabielDavid M,KulurVrishika,CoelhoAna Lucia,DengNan,XieTing,WangYizhou,LiuNingshan,HuangGuanling,KurkciyanAdrianne,LiuZhenqiu,TangJie,HogaboamCory M,JiangDianhua,NoblePa
Journal: JCI Insight
PubMed ID: 30763282
Doi: 10.1172/jci.insight.125326
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